Nogales Bus Station: Bus Routes from Nogales, Arizona to Mexico

Nogales Bus Station is an important departure point for travelers crossing the United States–Mexico border and continuing their journey toward northwestern Mexico. Located in southern Arizona, Nogales provides access to international bus routes connecting the United States with destinations in Sonora, Sinaloa, Nayarit and Jalisco.
Passengers looking for a bus from Nogales, Arizona to Mexico can find two important transportation operators in the city: TUFESA Internacional and Greyhound. Each company serves a different type of journey. TUFESA offers international bus services toward Mexico, while Greyhound provides connections within the United States.
The location of Nogales makes it particularly convenient for passengers traveling toward Hermosillo, Ciudad Obregón, Los Mochis, Culiacán, Mazatlán, Tepic and Guadalajara.
This guide to Nogales Bus Station includes terminal addresses, phone numbers, Google Maps locations, bus companies, direct routes, estimated travel times and ticket prices. It also explains what passengers should know before crossing the international border and continuing by bus into Mexico.
Bus Stations and Departure Points in Nogales, Arizona
There are two main bus departure locations included in this Nogales, Arizona bus station guide:
TUFESA Internacional: 213 N Grand Ave, Nogales, AZ 85621, United States.
Greyhound: 82 N Terrace Ave, Nogales, AZ 85621, United States.
These are separate departure points used by different transportation companies. TUFESA is particularly relevant for international bus routes to Mexico, while Greyhound serves passengers traveling within the United States.
Before traveling, check the departure address printed on your ticket. Do not assume that both companies use the same terminal or that a ticket purchased with one operator includes transportation with the other.
1. TUFESA Internacional
TUFESA Internacional is one of the main bus companies operating in Nogales, Arizona, for passengers traveling from the United States to Mexico.
Its terminal on North Grand Avenue provides access to international bus routes toward Sonora and other destinations along Mexico's Pacific transportation corridor.
For passengers looking for Nogales Bus Station services to Mexico, TUFESA is the main operator to consider when comparing direct international bus routes and longer-distance journeys.
TUFESA Bus Station in Nogales, Arizona
Address: 213 N Grand Ave, Nogales, AZ 85621, United States.
Phone: +1 520-287-9977.
Official website: TUFESA Internacional.
Google Maps: View TUFESA Bus Station in Nogales.
Location: Near the international border crossing in downtown Nogales.
TUFESA identifies its Nogales, Arizona location as a large terminal with a waiting area, restrooms, Wi-Fi and parking facilities. Its published terminal directory lists the location as operating 24 hours, although passengers should confirm ticket-office and boarding arrangements before traveling.
The terminal is an important departure point for passengers looking for a bus from Nogales, Arizona to Hermosillo, Ciudad Obregón and other Mexican destinations.
How Does the TUFESA Border Crossing Work?
One important detail about traveling with TUFESA from Nogales, Arizona to Mexico is the international border procedure.
According to the route information provided for this guide, passengers travel from the Arizona terminal toward the Nogales international crossing. At the Mexican customs and immigration checkpoint, passengers must follow the instructions of border authorities and complete the required inspections.
Passengers may be asked to leave the bus and present their luggage for inspection. On itineraries operated with the same vehicle throughout the journey, passengers can reboard the bus after completing the border procedures.
This means that a border inspection does not necessarily represent a scheduled vehicle transfer. However, the exact procedure depends on the service and itinerary purchased.
Before booking, confirm whether the bus continues with the same vehicle after the border or whether passengers must change units.
Direct Bus Routes from Nogales, Arizona to Mexico
TUFESA connects Nogales, Arizona with several important destinations in northwestern Mexico. Its routes provide access to Sonora, Sinaloa, Nayarit and Jalisco.
The following destinations, estimated durations and prices are useful reference points when planning a journey from Nogales Bus Station.
The prices and travel times below are indicative estimates, not guaranteed current fares or schedules. Confirm the exact information with TUFESA before purchasing your ticket.
Bus from Nogales, AZ to Hermosillo, Sonora
Destination: Hermosillo, Sonora.
Estimated duration: 4 hours 15 minutes to 5 hours.
Indicative price: USD $40–$46.
Approximate price in Mexican pesos: MXN $750–$880.
Hermosillo is one of the main destinations for passengers traveling from Nogales, Arizona to Mexico. As the capital of Sonora, it is an important transportation center for journeys toward other cities in the state.
The Nogales–Hermosillo bus route is particularly useful for travelers visiting the state capital, connecting with family or continuing toward other destinations in northwestern Mexico.
Bus from Nogales, AZ to Ciudad Obregón, Sonora
Destination: Ciudad Obregón, Sonora.
Estimated duration: 7–8 hours.
Indicative price: USD $55–$65.
Approximate price in Mexican pesos: MXN $1,050–$1,250.
Ciudad Obregón is an important urban destination in southern Sonora. Passengers traveling from Nogales can use this connection to reach the Yaqui Valley and continue toward other cities in the region.
The Nogales–Ciudad Obregón bus route is relevant for travelers heading farther south within Sonora without first arranging a separate trip from another Arizona city.
Bus from Nogales, AZ to Los Mochis, Sinaloa
Destination: Los Mochis, Sinaloa.
Estimated duration: 10 hours 30 minutes to 11 hours.
Indicative price: USD $80–$92.
Approximate price in Mexican pesos: MXN $1,500–$1,750.
Los Mochis is one of the main destinations in northern Sinaloa and an important connection point for travelers continuing through the Pacific region of Mexico.
Passengers traveling from Nogales to Los Mochis can use this route to reach northern Sinaloa and explore further transportation connections toward other cities in the state.
Bus from Nogales, AZ to Culiacán, Sinaloa
Destination: Culiacán, Sinaloa.
Estimated duration: 14–15 hours.
Indicative price: USD $90–$105.
Approximate price in Mexican pesos: MXN $1,700–$2,000.
Culiacán is the capital of Sinaloa and one of the main destinations along the Pacific transportation corridor.
The Nogales–Culiacán bus connection is useful for passengers traveling from southern Arizona toward central Sinaloa. The longer journey makes it particularly important to check the departure schedule, arrival time and ticket conditions before traveling.
Bus from Nogales, AZ to Mazatlán, Sinaloa
Destination: Mazatlán, Sinaloa.
Estimated duration: 17–18 hours.
Indicative price: USD $105–$120.
Approximate price in Mexican pesos: MXN $2,000–$2,300.
Mazatlán is an important coastal destination in southern Sinaloa. Its location on the Pacific coast makes it relevant for passengers traveling from Arizona toward Mexico's western coastal region.
The Nogales–Mazatlán bus route is a longer-distance journey. Passengers should compare departure times and confirm whether the selected itinerary operates directly or includes intermediate stops.
Bus from Nogales, AZ to Tepic, Nayarit
Destination: Tepic, Nayarit.
Estimated duration: 21–22 hours.
Indicative price: USD $125–$140.
Approximate price in Mexican pesos: MXN $2,350–$2,650.
Tepic is the capital of Nayarit and an important destination for travelers continuing south from Sonora and Sinaloa.
The Nogales–Tepic bus connection provides access to western Mexico and can be useful for passengers visiting the state of Nayarit or continuing toward Jalisco.
Bus from Nogales, AZ to Guadalajara, Jalisco
Destination: Guadalajara, Jalisco.
Arrival: Nueva Central Camionera de Guadalajara.
Estimated duration: 24–25 hours.
Indicative price: USD $135–$150.
Approximate price in Mexican pesos: MXN $2,550–$2,850.
Guadalajara is one of the most important destinations in western Mexico and the capital of Jalisco.
The Nogales–Guadalajara bus route connects southern Arizona with one of Mexico's largest metropolitan areas. Passengers arriving at the Nueva Central Camionera can continue their journey toward other destinations in Jalisco and neighboring states.
Because this is a long-distance international journey, check the arrival terminal, total travel time and any intermediate stops before booking.
2. Greyhound Bus Station in Nogales, Arizona
Greyhound is another bus company with a departure location in Nogales, Arizona. Unlike TUFESA, its services from this location are primarily relevant for passengers traveling within the United States.
The Greyhound station provides an option for travelers who need to connect Nogales with other U.S. cities before continuing their journey.
Passengers should distinguish between a Greyhound domestic itinerary and an international bus journey into Mexico. A Greyhound ticket to Nogales, Arizona does not automatically include transportation from the border into Nogales, Sonora or onward to other Mexican destinations.
Greyhound Bus Station in Nogales
Address: 82 N Terrace Ave, Nogales, AZ 85621, United States.
Phone: +1 800-231-2222.
Official website: Greyhound.
Google Maps: View Greyhound Bus Station in Nogales.
The Greyhound location is separate from the TUFESA terminal on North Grand Avenue. Passengers should check their ticket to confirm the correct boarding point.
Greyhound Connections and the Border Crossing
Greyhound and TUFESA operate different transportation networks in Nogales.
Travelers arriving at the Greyhound station should not assume that the same Greyhound vehicle continues into Mexico. Depending on the ticket and available connections, passengers may need to complete the border crossing separately and arrange another bus service on the Mexican side.
If you plan to continue toward Hermosillo, Ciudad Obregón, Culiacán or Guadalajara, check the complete itinerary before departure.
In particular, confirm the location of the Mexican departure terminal, the time required to cross the border and whether you need a separate ticket for the onward journey.
Main Bus Routes from Nogales, Arizona to Mexico
Nogales is an important starting point for journeys into northwestern Mexico. Its international bus connections provide access to several states along the Pacific transportation corridor.
Routes from Nogales to Sonora
Sonora is the main Mexican state connected with Nogales, Arizona.
The principal destinations included in this guide are:
Nogales, Sonora.
Hermosillo.
Ciudad Obregón.
Hermosillo is particularly important for passengers continuing toward central Sonora, while Ciudad Obregón provides access to the southern part of the state.
Routes from Nogales to Sinaloa
Passengers traveling farther south can reach destinations in Sinaloa, including:
Los Mochis.
Culiacán.
Mazatlán.
These cities connect Nogales with northern, central and southern parts of Sinaloa.
The Nogales–Los Mochis, Nogales–Culiacán and Nogales–Mazatlán routes are useful for travelers heading toward the Mexican Pacific coast and the state's main urban centers.
Routes from Nogales to Nayarit
Tepic is the main destination in Nayarit included in this guide.
Passengers traveling from Nogales to Tepic can continue their journey toward other destinations in the state or use additional connections toward western Mexico.
Routes from Nogales to Jalisco
Guadalajara is the main destination in Jalisco included in this directory.
The route from Nogales to Guadalajara connects Arizona with one of Mexico's most important metropolitan areas and provides onward transportation options toward other cities in western Mexico.
Direct Bus Routes and Journeys Requiring Transfers
When booking a bus from Nogales, Arizona to Mexico, it is important to understand the difference between a direct route and an itinerary involving a transfer.
A direct route generally means that passengers travel on the same bus between the departure and arrival cities, although border inspections and intermediate stops may take place.
A connecting itinerary involves leaving one vehicle and boarding another to continue toward the final destination.
TUFESA Direct International Routes
TUFESA operates international bus services from Nogales, Arizona toward destinations in Mexico.
For the routes listed in this guide, passengers should verify whether the selected service continues with the same bus after the international border crossing.
Border authorities may require passengers to leave the vehicle and collect their luggage for inspection. This procedure does not necessarily mean that the journey involves a change of bus.
Greyhound and Separate Connections to Mexico
Greyhound should be considered separately when planning a journey from Nogales, Arizona to Mexico.
Passengers using Greyhound may need to complete the international crossing independently and purchase a separate ticket for the Mexican part of their journey.
This is particularly important when comparing the total travel time and cost of a trip to destinations such as Hermosillo, Los Mochis, Culiacán or Guadalajara.
Before booking, confirm:
Whether the journey is direct.
Whether you need to change buses.
Where the transfer takes place.
Whether you must collect your luggage.
Whether the onward service departs from another terminal.
Whether the complete journey is covered by one ticket.
How to Choose the Right Bus Station in Nogales
Choosing the correct bus station depends on your final destination and the company operating your selected service.
Choose TUFESA for Routes to Mexico
TUFESA is the main option covered in this guide for passengers traveling from Nogales, Arizona toward Sonora, Sinaloa, Nayarit and Jalisco.
Its North Grand Avenue terminal provides access to international bus services and longer-distance routes into Mexico.
Choose Greyhound for U.S. Connections
Greyhound is relevant for passengers traveling within the United States from Nogales.
If your final destination is in Mexico, check how you will cross the border and where you can board your next bus.
Compare Travel Times and Ticket Prices
A direct international bus route may be more convenient than an itinerary involving separate domestic and international services.
Compare the total journey time, number of transfers, ticket conditions and arrival location before making your reservation.
Important Information Before Traveling from Nogales, Arizona to Mexico
International bus journeys require additional preparation.
Travel Documents
Passengers crossing into Mexico must carry the travel documents required for their nationality and immigration status.
A valid passport and, depending on the circumstances, additional immigration documentation may be necessary. Check the official requirements before traveling.
Border and Customs Inspections
Passengers entering Mexico must complete the applicable immigration and customs procedures.
During the crossing, authorities may ask passengers to leave the bus and present their luggage for inspection.
Follow the instructions of the bus company and border officials throughout the process.
Luggage Allowance
Baggage conditions vary between transportation companies and ticket types.
Before traveling, check the number of permitted bags, maximum weight and any additional charges.
For international routes, keep your travel documents and valuables accessible during the border inspection.
Arrival Time at the Terminal
Arrive early at your departure location, especially if you need to collect a physical ticket, check your luggage or confirm your boarding details.
Allowing approximately 45 minutes before departure is a useful planning reference, but always follow the arrival instructions provided by the operator.
Frequently Asked Questions About Nogales Bus Station
Which bus companies operate in Nogales, Arizona?
The two companies included in this guide are TUFESA Internacional and Greyhound. TUFESA provides international routes toward Mexico, while Greyhound serves domestic connections within the United States.
Where is TUFESA Bus Station in Nogales, Arizona?
TUFESA is located at 213 N Grand Ave, Nogales, AZ 85621, United States. You can find the location using Google Maps.
Where is Greyhound Bus Station in Nogales, Arizona?
Greyhound is located at 82 N Terrace Ave, Nogales, AZ 85621, United States. Its location is available on Google Maps.
Can I travel directly from Nogales, Arizona to Hermosillo?
Yes. TUFESA lists connections between Nogales, Arizona and Hermosillo, Sonora. Check the selected departure to confirm the travel time and whether the same vehicle continues after the border inspection.
Can I travel from Nogales to Guadalajara by bus?
Yes. TUFESA offers connections from Nogales toward Guadalajara, Jalisco. The estimated journey is approximately 24–25 hours, depending on the service and route.
How long does the bus from Nogales to Hermosillo take?
The estimated journey is approximately 4 hours 15 minutes to 5 hours, although the actual duration depends on the departure and border procedures.
Does Greyhound provide direct bus services to Mexico from Nogales?
Do not assume that a Greyhound domestic service continues directly into Mexico. Check the ticket and arrange the Mexican part of the journey separately if required.
How early should I arrive at Nogales Bus Station?
Arriving approximately 45 minutes before departure is a useful reference for international travel. Check the instructions on your ticket because some departures may require additional time.
Related Bus Stations in the United States
Travelers looking for other departure points and international bus routes can explore our guides to additional cities and states.
Arizona Bus Stations
Other State Bus Station Directories
These guides help travelers compare departure cities, find bus companies and discover transportation options between the United States and Mexico.
Plan Your Bus Trip from Nogales, Arizona to Mexico
Nogales Bus Station is an important departure point for passengers traveling from Arizona to Mexico. With TUFESA Internacional offering international bus services and Greyhound providing domestic connections, travelers have different options depending on their destination.
TUFESA is particularly relevant for passengers heading toward Hermosillo, Ciudad Obregón, Los Mochis, Culiacán, Mazatlán, Tepic and Guadalajara.
Before booking your bus from Nogales, Arizona to Mexico, compare departure locations, schedules, estimated fares and transfer arrangements. Make sure you understand the border procedures and confirm whether your journey continues on the same vehicle.
Use this Mexicanote guide to find the right Nogales bus station, compare transportation companies and plan your next journey from the United States to Mexico.
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